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固有淋巴细胞在肿瘤形成中的作用 被引量:1

The role of innate lymphoid cells in tumorigenesis
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摘要 先天淋巴细胞(ILCs)是一类新近发现的在粘膜免疫中发挥重要功能的固有免疫细胞。最新研究证实它们在肿瘤发生、发展过程中扮演着重要角色。在此我们综述ILCs与几种肿瘤形成的关系,以期为癌症的预防和治疗提供新的理论借鉴。 Innate lymphoid cells (ILCs) are innate immune cells, which play an important role in the mucosal immunity. ILCs play an important role in the defense against pathogens, tissue development and remodeling. Recent research indicates that ILCs also play an important role in tumorigenesis. This article describes the relationship between ILCs and a variety of tumorigenesis, providing a new theoretical reference for the prevention and treatment of cancer.
出处 《免疫学杂志》 CAS CSCD 北大核心 2015年第7期628-632,共5页 Immunological Journal
基金 国家自然科学基金国际(地区)合作与交流项目(81220108024) 第三军医大学青年人才创新基金(2011XQN04)
关键词 先天淋巴样细胞 细胞因子 肿瘤 Innate lymphoid cells Cytokine Cancer
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  • 1Constantinides MG, McDonald committed precursor to innate 2014, 508(7496): 397-401.
  • 2BD, Verhoef PA, et al. A lymphoid cells [J]. Nature, Montaldo E, Vacca P, Moretta L et al. Development of human natural killer ceils and other innate lymphoid cells[J]. Semin Immunol, 2014, 26(2): 107-113.
  • 3Serafini N, Klein Woherink RG, Satoh Takayama N, et al. Gata3 drives development of ROR'yt ~ group 3 innate lymphoid cells[J]. J Exp Med, 2014, 211(2): 199-208.
  • 4Fuchs A, Colonna M. Innate lymphoid cells in homeostasis, infection, chronic inflammation and tumors of the gastrointestinal tract[J]. Curr Opin Gastroenterol, 2013, 29(6): 581-587.
  • 5Spits H, Artis D, Colonna M, et al. Innate lymphoid cells - a proposal for uniform nomenclature[J]. Nat Rev Immunol, 2013, 13(2): 145-149.
  • 6Spits H, Cupedo T. Innate lymphoid cells: emerging insights in development, lineage relationships, and function[J]. Annu Rev Immunol, 2012, 30: 647-675.
  • 7Leavy O. Innate-like lymphoeytes: Will the real ILC1 please stand up.'? [J]. Nat Rev Immunol, 2013, 13(2): 67.
  • 8Klose CSN, Flach M, Mohle L, et al. Differentiation of type 1 ILCs from a common progenitor to all helper-like innate lymphoid cell lineages[J]. Cell, 2014, 157(2): 340-356.
  • 9Furusawa J, Moro K, Motomura Y, et al. Critical role of p38 and GATA3 in natural helper cell function[J]. J Immunol, 2013, 191(4): 1818-1826.
  • 10Fort MM, Cheung J, Yen D, et al. IL-25 induces IL-4, IL- 5, and IL-13 and Th2-associated pathologies in vivo[J]. Immunity, 2001, 15(6): 985-995.

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