摘要
To tile Editor： We have read with interest the article reported by Guo et al.,Hlwho performed a transoral thyroidectomy with central neck dissection on human cadavers by using a sublingual combined bilateral vestibular access. Interestingly, the described technique is identical to our approach that we published as a video paper in 2009.t21 Although we could demonstrate tile surgical feasibility of a total transoral thyroidectomy as early as 2008, we still had concerns about its clinical application, e.g., floor of mouth and specimen volume, manipulation of instruments, visualization of the recurrent laryngeal nerve, and risk o1＇ mental nerve lesion by the lateral vestibulum trocar. Therefore, we decided not to proceed to clinical application before further preclinical investigation results were available. One group did not share our view and applied this technique on eight human beings where they encountered above cited concerns resulting in severe complications, such as paresthesia of the mental nerve （6/8 patients）, conversion to open surgery due to specimen size （3/8 patients）, palsy of the rectirrent laryngeal nerve （2/8 patients; one permanent） and local streptococci infection at the vestibular incision site necessitating surgical revision.TM These serious adverse events finally lbrced this group to stop their clinical study. Another group recently published the results of their pilot study on 5 patients with primary hyperparathyroidisrn who underwent a transoral parathyroidectomy.141 In two patients, the procedure had to be converted to the conventional technique. One patient had transient recurrent laryngeal nerve palsy, while one patient suffered from a transient palsy of the right hypoglossal nerve with persisting dysgeusia. Three patients developed swallowing problems. In four patients, the visual analog scale pain score was high. Also here, the authors terminated their study because of the high complication rate.
To tile Editor： We have read with interest the article reported by Guo et al.,Hlwho performed a transoral thyroidectomy with central neck dissection on human cadavers by using a sublingual combined bilateral vestibular access. Interestingly, the described technique is identical to our approach that we published as a video paper in 2009.t21 Although we could demonstrate tile surgical feasibility of a total transoral thyroidectomy as early as 2008, we still had concerns about its clinical application, e.g., floor of mouth and specimen volume, manipulation of instruments, visualization of the recurrent laryngeal nerve, and risk o1＇ mental nerve lesion by the lateral vestibulum trocar. Therefore, we decided not to proceed to clinical application before further preclinical investigation results were available. One group did not share our view and applied this technique on eight human beings where they encountered above cited concerns resulting in severe complications, such as paresthesia of the mental nerve （6/8 patients）, conversion to open surgery due to specimen size （3/8 patients）, palsy of the rectirrent laryngeal nerve （2/8 patients; one permanent） and local streptococci infection at the vestibular incision site necessitating surgical revision.TM These serious adverse events finally lbrced this group to stop their clinical study. Another group recently published the results of their pilot study on 5 patients with primary hyperparathyroidisrn who underwent a transoral parathyroidectomy.141 In two patients, the procedure had to be converted to the conventional technique. One patient had transient recurrent laryngeal nerve palsy, while one patient suffered from a transient palsy of the right hypoglossal nerve with persisting dysgeusia. Three patients developed swallowing problems. In four patients, the visual analog scale pain score was high. Also here, the authors terminated their study because of the high complication rate.
