肝硬化患者生存质量的影响因素

Factors associated with quality of life in patients with cirrhosis

目的:调查分析影响肝硬化患者生存质量的相关因素.方法:对昆明医科大学第一附属医院消化科住院的214例肝硬化患者采用中文版简明健康调查量表(Medical Outcomes Study Short Form36,SF-36)进行问卷调查,同时收集患者相关资料,采用单因素分析及多元逐步回归分析.结果:单因素分析影响肝硬化患者生存质量各个维度的因素分别是治疗费用占家庭收入比例、乏力、纳差、头晕、家庭经济负担、焦虑、抑郁(P<0.05);多元线性回归分析影响肝硬化患者生存质量总分的多因素分别为年龄、头晕、腹胀、焦虑、抑郁、家庭经济负担(P<0.05).结论:肝硬化患者生存质量的影响因素是复杂的,并且同时受多方面因素的影响.

AIM：To investigate and evaluate the factors related to the quality of life in patients with cirrhosis.METHODS：The quality of life for 214 cirrhosis patients treated at our hospital was assessed using the Chinese version of Medical Outcomes Study Short Form-36（SF-36） questionnaire.Relevant clinical data for patients were also collected to conduct univariate analysis and multivariate stepwise regression analysis.RESULTS：Univariate analysis showed that factors affecting the quality of life in all dimensions in patients with cirrhosis were percentage of treatment costs accounting for family income,fatigue,anorexia,dizziness,family economic burden,anxiety and depression（P〈0.05）.Multivariate linear regression analysis demonstrated that age,dizziness,loss of appetite,anxiety,depression,and family economic burden significantly affect the quality of life scores in patients with cirrhosis（P〈0.05）.CONCLUSION：The factors influencing the quality of life in patients with cirrhosis are complex and multifactorial.