内镜黏膜下剥离术后食管狭窄的防治新进展

Advances in prevention and treatment of esophageal stenosis after endoscopic submucosal dissection

内镜黏膜下剥离术(endoscopic submucosal dissection,ESD)是指利用各种电刀对>2 cm的病变进行黏膜下剥离的内镜微创技术,目前已经成为食管早癌及癌前病变的首选治疗方法.随着食管ESD技术的广泛应用及发展,ESD术后食管狭窄作为食管ESD术的一个主要并发症,影响了范围较大的食管早癌及癌前病变的内镜下治疗,一直困扰着国内外消化内镜专家.对于ESD术后食管狭窄,国际上尚无公认的治疗指南.不同国家的学者正在研究多种不同的治疗或预防方案,期待找到一种较好的解决ESD术后食管狭窄的治疗或预防方法.本文就ESD术后食管狭窄的防治新进展作一综述.

Endoscopic submucosal dissection（ESD）is one of endoscopic minimally invasive techniques,referring to submucosal dissection of lesions greater than 2 cm using a variety of electric scalpels.At present ESD has become the most common choice of treatment for early esophageal cancer and precancerous lesions.With the wide application and development of esophageal ESD technology,post-ESD esophageal stenosis,as a major complication of esophageal ESD,has affected endoscopic treatment for the larger scope of early esophageal cancer and precancerous lesions and has plagued digestive endoscopy experts.For this complication,there have been no universally accepted treatment guidelines in the world.Scholars of different countries are taking efforts to develop different treatment or prevention strategies,looking forward to finding a better solution to the treatment or prevention of this complication.In this paper,we focus on the recent progress in the prevention and treatment of post-ESD esophageal stenosis.