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肿瘤相关巨噬细胞计数、基质金属蛋白酶-2及Ki-67的表达与结直肠癌预后的关系 被引量:9

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摘要 结直肠癌是消化系统常见的恶性肿瘤之一,其病死率仅次于肺癌和乳腺癌。近年来,肿瘤相关巨噬细胞(tumor associated macrophage,TAM)成为研究热点,但在结直肠癌中研究鲜有报道。已有研究证实,恶性肿瘤中基质金属蛋白已有研究证实,恶性肿瘤中基质金属蛋白酶-2(matrix metalloproteinase-2,MMP-2)及细胞增殖相关蛋白Ki-67表达含量越高,细胞浸润转移、增殖能力越强,预后越差。
出处 《中华消化杂志》 CAS CSCD 北大核心 2015年第6期405-407,共3页 Chinese Journal of Digestion
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