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骨关节炎DNA甲基化研究进展

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摘要 骨关节炎（osteoarthritis，OA）是以关节软骨退变和关节周围骨质增生为病理特征的慢性进行性骨关节疾病．好发于中老年人群，而且随着年龄的增长发病率逐渐增高．据调查发现，其发生率约为3％。OA主要侵害关节软骨、骨和滑膜组织，导致关节疼痛、畸形和功能障碍，
作者 周天天 史晓薇 韩晶 郭雄
机构地区 西安交通大学医学院公共卫生学院地方病研究所卫生部微量元素与地方病重点实验室、环境与疾病相关基因教育部重点实验室 西安交通大学医学院第一附属医院
出处 《中华地方病学杂志》 CAS CSCD 北大核心 2015年第7期531-533,共3页 Chinese Journal of Endemiology
基金 国家自然科学基金（81273007、81472924）
关键词 骨关节炎 DNA甲基化 CPG岛 进展
分类号 R684.3 [医药卫生—骨科学]
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参考文献29

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二级参考文献65

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中华地方病学杂志
2015年 第7期

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