自拟中药祛疣方外洗治疗妊娠期尖锐湿疣的临床研究

Clinical research on traditional Chinese medicine of Quyoufang washout therapy on condyloma acuminatum in gestational period

目的:探讨采用中药外洗配合激光治疗妊娠期尖锐湿疣的临床疗效。方法:将58例妊娠期尖锐湿疣患者按随机数字表法分为治疗组30例和对照组28例,治疗组采用CO2激光祛除瘤体后,再用自拟中药方熏洗;对照组单纯采用CO2激光治疗。结果:治疗组有效率为90%,对照组有效率为75%,两组有效率比较,差异有统计学意义(P<0.05)。两组患者复发率比较差异有统计学意义(P<0.05)。两组患者妊娠结局及围产儿结局情况比较,差异无统计学意义(P>0.05)。结论:中药外洗配合激光治疗妊娠期尖锐湿疣疗效好,对孕妇及胎儿安全,不良反应少,值得在临床应用。

Objectives： To study the curative effect of traditional Chinese medicine washout combined with laser therapy on condyloma acuminatum in gestational period. Methods： 58 cases of condyloma acuminatum were divided into treatment group （ n = 30） and control group （ n = 28） according to random digits table. The treatment group was given traditional Chinese medicine washout after CO2 laser treatment. The control group was only given CO2 laser treatment. Results ： The effective rate was 90% in treatment group and 75% in control group, with statis- tically significant difference （P 〈 0. 05 ）. The differences in pregnancy outcome and perinatal infants situation be- tween the two group wasn＇t statistically significant （P 〉 0. 05）. Conclusions： Traditional Chinese medicine wash- out combined with laser therapy for condyloma acuminatum in gestational period has curative effect with fewer ad- verse reaction, which is worthy of clinical application.