支原体感染与不孕症相关影响因素的研究

Study on the influencing factors of mycoplasma infection of female infertility

目的:探索研究女性支原体感染对不孕症的具体影响。方法:选择我院收治的不孕患者240例作为研究组,同时选择在我院接受健康体检的非不孕妇女共计240例作为对照组,对两组对象进行支原体检测并对相关因素进行对比判断。结果:研究组患者的解脲支原体阳性率为36.67%,显著高于对照组研究对象的13.34%(P<0.05);原发不孕患者解脲支原体阳性率为34.29%,继发不孕患者则为39.00%,组间差异不具有统计学意义(P>0.05);不孕患者支原体对罗红霉素的耐药率高达56.25%,对强力霉素的敏感率高达87.50%,对克拉霉素的敏感率为77.92%,对氧氟沙星的敏感率为75%。结论:支原体感染与女性不孕具有极为密切的关系,其具体致病机制还需深入研究,为预防和治疗提供科学依据。

Objectives： To explore the influencing factors of mycoplasma infection of female infertility. Meth- otis： 240 infertility patients in our hospital were selected as study group and 240 eases of non-infertile women were se- lected as control group. Mycoplasnm test on two groups was done and the relevant factors were compared. Results： The positive rate of ureaplasma urealyticum （Uu） in patients of the study group was 36.67%, which was significantly higher than that in the control group （ 13.34% ） （ P 〈 0. 05）. The positive rate of Uu in primary infertility patients was 34.29% and the positive rate of Uu in secondary infertility patients was 39%. The difference between groups was not statistically significant （P 〉0. 05）. Mycoplasma resistance rate of roxithromycin in infertility patiems was as high as 56. 25%; the rate of susceptibility to doxycycline was as high as 87.50% ; the sensitive rate of clarithromycin was 77.92% and the rate of susceptibility to ofloxacin was 75%. Conclusions： Mycoplasma infection is very close related to female infertility, and the specific pathogenesis needs further studied to provide scientific basis for prevention and treatment of infertility.