子宫动脉栓塞术对产后出血患者卵巢功能的远期影响分析

The long- term impact of uterine arterial embolization on the ovarian function of patients with postpartum hemorrhage

目的：探讨子宫动脉栓塞治疗对产后出血患者卵巢功能的远期影响,为其临床应用提供可参考依据。方法：选择60例我院诊断为产后出血的产妇,所有患者均行子宫动脉栓塞术治疗,随访1年观察患者的疗效,并分析其对卵巢功能的远期影响。结果：38例产妇月经复潮在术后3个月内占63.3%,19例月经复潮在术后4-8个月内占31.7%,3例月经复潮在术后9-12月内占5.0%。术后3个月、6个月、12个月与术前比较,月经周期延长、月经量增多患者均明显减少,差异有统计学意义（P〈0.05）。与术前相比,术后3个月、6个月、12个月E2、P、FSH、LH、PRL水平无明显变化,差异比较无统计学意义（P〉0.05）。结论：子宫动脉栓塞对治疗产后出血患者并未造成长期的月经异常,且术后对卵巢功能的影响不明显,手术的长期预后较好,值得临床推广应用。

Objectives： To analyze the long - term impact of uterine arterial embolization on the ovarian func- tion of patients with postpartum hemorrhage after interventional treatment. Methods： 60 patients with postpartum hem- orrhage were included. All patients were given interventional treatment and followed up for 1 year to analyze the long -term impact for ovarian function. Results： 38 patients had menstruation 3 months after surgery, accounting for 63. 3% ; 19 patients had menstruation 4 to 8 months after surgery, accounting for 31.7% ; 3 patients had menstruation 9 to 12 months after surgery, accounting for 5.0%. The number of patients whose menstrual cycle was extended and menstrual quantity was increased significantly reduced 3 months, 6 months and 12 months after the surgery, with sta- tistically significant difference （P 〈 0. 05）. The differences in E2, P, FSH, LH, and PRL after 3 months, 6 months, 12 months were not significant （P 〉 0. 05 ）. Conclusions： Uterine artery embolization cannot cause long- term men- strual abnormalities nor have obvious influence on the ovarian function of patients with postpartum hemorrhage.