探讨乳腺纤维肉瘤的病理诊断

Explore the Pathological Diagnosis ot Mammary Gland Fibrosarcoma

目的分析乳腺纤维肉瘤的病理特点、鉴别诊断。方法收集我院2013年11月诊治的1例乳腺纤维肉瘤病患者作为研究对象,对患者实施组织学和免疫组化观察,总结患者的病理特点。结果研究结果显示,Actin和desmin少数细胞阳性,瘤细胞vimentin和SMA阳性,EMA、ER、CD34、PR、CK5/6、AE1/AE3、S-100蛋白均阴性,K-i 67阳性细胞在百分之五以内。结论乳腺纤维肉瘤通过组织病理学诊断可明确病情,但需要注意与梭形细胞癌、肌纤维母细胞瘤、肌上皮癌、结节性筋膜炎、纤维肉瘤和乳腺反应性梭形细胞结节等病灶的区分。

Objective To analyze pathological features, differential diagnosis of mammary gland fibrosarcoma. Methods Collected from November 2013, diagnosis and treatment of mammary gland fibrosarcoma 1 case patients as the research object, for patients with histological and immunohistochemical observations, summed up the pathological changes of patients. Results The results showed that the Actin and minority cells desmin positive, vimentin and SMA positive tumor cells, EMA, ER, CD34, PR, CK5/6, AE1 / AE3, S- 100 protein were negative, K- 67 positivecells in five percent less than I. Conclusion Mammary gland fibrosarcoma can be clearly diagnosed by histopathology, but need to pay attention to and spindle cell carcinoma, muscle fiber mother cell tumor, myoepithelial carcinoma, nodular fasciitis, fibrosarcoma and mammary gland of reactive nodular lesions such as spindle cells.