甘精胰岛素与阿卡波糖联合应用治疗糖尿病肾病120例临床疗效分析

Clinical Effect Analysis on Glargine Insulin Combined With Acarbose for the Treatment of 120 Cases Diabetic Nephropathy

目的探讨甘精胰岛素与阿卡波糖联合应用治疗糖尿病肾病临床疗效。方法随机选取2009年11月~2011年11月份因糖尿病肾病就诊于我院的患者进行治疗的患者200例,随机分为治疗组120例患者（甘精胰岛素与阿卡波糖联合应用治疗）,对照组80例患者（诺和灵30R治疗）,观察两组治疗前后空腹血糖的变化及餐后2 h血糖的变化,并对结果进行统计分析。结果治疗组治疗后空腹血糖为（4.35±1.2）mmol/L,餐后两小时血糖为（7.42±2.3）mmol/L,治疗效果好于对照组,经统计分析,P〈0.05,差异存在显著性。结论甘精胰岛素与阿卡波糖联合应用治疗糖尿病肾病能够有效控制患者的血糖情况。

Objective To discuss the clinical effect of glargine insulin combined with acarbose for the treatment of diabetic nephropathy. Methods From November, 2009 to November, 2011, 200 patients with diabetic nephropathy were randomly selected in our hospital, they were randomly divided into treatment group（glargine insulin combined with acarbose treatment） 120 cases and control group（Novolin 30 R treatment） 80 cases, fasting blood glucose and 2 hours postprandial blood glucose were observed before and after treatment in two groups, and the results were statistically analyzed. Results After treatment, in treatment group, the fasting blood glucose was（4.35±1.2） mmol / L, two hour postprandial blood glucose was（7.42±2.3） mmol / L, the treatment effect was significantly better than the control group, after statistical analysis, P〈0.05, there was statistical significance. Conclusion Glargine insulin combined with acarbose fortreatment of diabetic nephropathy can effectively control the blood glucose.