绝经后女性骨密度与心血管疾病的关系

Bone mineral density and cardiovascular disease in postmenopausal women

骨密度是评价骨量变化、预测骨质疏松骨折风险的最佳指标。骨组织受性激素调节，绝经后女性雌激素水平与骨密度下降及心血管疾病风险增加密切相关。但是，骨密度能否预测心血管疾病的风险，以及这一作用是否与内源性的雌激素相关尚无定论。本文对此方面的研究现状作简要介绍。

It has been widely recognized that bone mineral density （BMD） is one of the best predictors of osteoporosis. Sex hormone status clearly affects bone either directly or indirectly. A longer estrogen exposure appears to be a major determinant of postmenopausal BMD and cardiovascular disease（CYD）. However, there was insufficient evidence to draw conclusions that BMD might be used as a predictor factor of the risk of CVD. Therefore, the aim of the review was to examine the existing evidence on the association between BMD and risk of CVD, and to address the issue of a putative common pathogenic factor of estrogen deficiency.