连续硬膜外阻滞联合臭氧治疗颈源性头痛的疗效分析

Investigation the treatment of the continuous epidural block combined with ozone to cervicogenic headache

目的探讨连续硬膜外腔阻滞联合臭氧硬膜外腔注射治疗颈源性头痛的临床疗效。方法诊断为颈源性头痛的患者40例,随机分为连续硬膜外腔阻滞组(E组)和连续硬膜外腔阻滞联合臭氧注射组(EO组)。两组患者接受持续硬膜外注射治疗3周,EO组每48小时给予硬膜外腔臭氧注射,每次10ml(30μg/ml),记录两组治疗前及治疗后1和2周及1、3、6个月的治疗效果,采用VAS评分及其改良Macnab疗效评定标准评价各时点的治疗优良率。结果与治疗前比较,治疗后两组VAS评分明显降低(P<0.05);EO组在治疗后1、3和6个月时VAS评分均明显低于E组(P<0.05)。治疗后1、3和6个月时EO组的治疗优良率明显高于E组(P<0.05)。结论连续硬膜外腔阻滞联合臭氧治疗颈源性头痛,远期效果优于单纯连续硬膜外腔阻滞,值得临床选用。

Objective To study the treatment effect of continuous epidural block with ozone for cervicogenic headache.Methods Forty cases of our hospital,October 2012 to October 2013 in the diagnosis of patients with cervicogenic headache.These patients in accordance with the principle of random divided into continuous epidural space anesthesia group（group E）and continuous epidural space block with ozone group（group EO）,group E age（51.3±7.2）years,group EO age（52.6±8.1）years.Two groups received the treatment with 3weeks,group EO give epidural space ozone injection every 48 h,10ml（30μg/ml）.Record the treatment effect of each patient before and after 1weeks,2weeks,1monthes,3monthes and 6monthes.Using visual analogue scale（VAS）and Macnab efficacy evaluation to evaluate the treatment effect.Results After the treatment,the VAS score in two groups were lower than before,and were significantly statistical difference compared with before treatment（P〈0.05）;In 1months,3months and 6months after the treatment,the VAS of group EO were lower than that of group E（P〈0.05）.After 1months,3months and 6months,total effective rate of group EO,were higher than those in group E（P〈0.05）.Conclusion To sum up,continuous epidural block with ozone can effectively cure cervicogenic headache,and compared with the continuous epidural block method,the long-term follow-up result is better.It is a source of more effective combination therapy method for cervicogenic headache,and should strengthen in the clinical treatment.