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miRNA调控Th细胞分化的研究进展 被引量:4

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摘要 未致敏的CD4+T细胞通过接受TCR抗原识别信号和共刺激信号,活化为不同的细胞亚群,如Th1、Th2、Th17、Treg、Tfh,参与宿主的适应性免疫应答。多种因素包括miRNA参与了Th细胞的发育过程,免疫异常调控会引起一系列的过敏及自身免疫性疾病等病理效应。本文就miRNA所涉及的调控网络对Th细胞的分化水平的影响进行了综述。
出处 《现代免疫学》 CAS CSCD 北大核心 2015年第4期334-337,共4页 Current Immunology
基金 上海市科委基础研发重点项目(11J1411602) 上海市教委科研创新重点项目(12ZZ103)
关键词 MIRNA TH细胞分化
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