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狼疮肾炎的规范化治疗

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摘要 系统性红斑狼疮(SLE)是一种以多器官系统受累和多种自身抗体阳性为主要特征的系统性自身免疫性疾病,育龄期女性中发病率最高。尽管SLE可以出现多脏器受累,肾脏受累仍然是最为常见和最为突出的并发症,多年的研究发现约60%的SLE患者在病程中发生狼疮肾炎,并严重影响患者的预后。SLE累及肾脏导致肾小球肾炎,临床上主要表现为蛋白尿、镜下血尿、水肿、高血压,严重者发生肾功能不全。
作者 张卓莉
出处 《中国临床医生杂志》 2015年第7期7-10,共4页 Chinese Journal For Clinicians
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参考文献11

  • 1Glassock RJ. Reclassification of lupus glomerulonephritis:back to the future[ J]. J Am Soc Nephrol,2004( 15 ) :501-503.
  • 2Weening JJ, D' Agati VD, Schwartz MM, et al. The classification of glomerulonephritis in systemic lupus etythematosus revisited [ J ].Kidney International,2004(65) :521-530.
  • 3Chan TM, Li FK,Tang CS, et al. Efficacy of mycophenolate mofetil in patients with diffuse proliferative lupus nephritis. Hong Kong- Guangzhou Nephrology Study Group [ J ]. N Engl J Med, 2000,343 (16) :1156-1162.
  • 4Ong LM, Hooi LS, Lim TO, et al. Randomized controlled trial of pulse intravenous cyclophosphamide versus mycophenolate mofetil in the induction therapy of proliferative lupus nephritis[J]. Nephrology (Carlton) ,2005,10( 5 ) :504-510.
  • 5Appel GB, Contreras G, Dooley MA, et al. Mycophenolate mofetil versus cyclophosphamide for induction treatment of lupus nephritis [J]. J Am Soc Nephrol,2009,20(5) :1103-1112.
  • 6Ginzler EM, Dooley MA, Aranow C, et al. Myeophenolate mofetil or intravenous cyclophosphamide for lupus nephritis [ J ]. N Engl J Med,2005,353 (21) :2219-2228.
  • 7Ding L,Zhao M,Zou W,et al. Mycophenolate mofetil combined with prednisone for diffuse proliferative lupus nephritis: a histopathologi- eal study[ J] Lupus,2004,13(2) :ll3.
  • 8Touma Z, Gladman DD, Urowitz MB, et al. Mycophenolate mofetil for induction treatment of lupus nephritis: a systematic review and meta analysis[J]. J Rheumatol,2011,38( 1 ) :69-78.
  • 9Hahn BH, Mcmahon MA, Wilkinson A, et al. American College of Rheumatology guidelines for screening, treatment, and management of lupus nephritis [J]. Arthritis Care Res ( Hoboken), 2012,64 (6) :797-808.
  • 10Contreras G, Pardo V, Leelercq B, et al. Sequential therapies for proliferative lupus nephritis [ J ]. N Engl J Med, 2004,350 ( 10 ) : 971-980.

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