普萘洛尔联合硝苯地平治疗中重型高血压疗效分析

Analysis of Combined Application of Propranolol and Nifedipine in the Treatment of Severe Hypertension

目的分析探讨硝苯地平与普萘洛尔联合对于中型和重型高血压的临床治疗效果。方法选择我院2014年1月~2014年12月之间收治的68例中重型高血压患者作为观察对象,所以患者在治疗前一周停止使用其他的降压药物。然后给药硝苯地平和普萘洛尔进行治疗,观察治疗前后的临床效果。结果全部68例患者在停药之前的有效率为45.58%,使用硝苯地平联合普萘洛尔之后的有效率为89.71%,差异具有统计学意义（P〈0.05）。结论对于中重型高血压患者应用硝苯地平联合普萘洛尔进行治疗具有较好的临床效果,且不良反应少。

Objective To explore the combination of nifedipine and propranolol for clinical treatment of moderate and severe hypertension. Methods 68 cases of patients with severe hypertension in our hospital from January December to 2014 were selected as the observation object, so the patients stopped using other antihypertensive drugs in the previous week. Then the administration of nifedipine and propranolol treatment, observe the clinical effect before and after treatment. Results All 68 cases patients before the withdrawal efficiency 45.58%. The use of nifedipine and propranolol after efficient 89.71%, the difference has statistical significance（P〈0.05）. Conclusion For the moderate and severe hypertensive patients were treated with nifedipine and propranolol treatment has better clinical effect and adverse reactions less, with good clinical application value.