乌司他丁治疗免疫功能降低并发急性间质性肺炎疗效分析

Ulinastatin in the Treatment of Immune Function Decreased with Acute Interstitial Pneumonia

目的探讨乌司他丁治疗免疫功能降低并发急性间质性肺炎的临床疗效。方法选择我院自2013年2月~2014年6月期间收治免疫功能降低并发间质性肺炎患者54例,根据患者的入院时间将本组54例患者平均分为对照组（n=27）和治疗组（n=27）,对照组患者接受盐水推注治疗,治疗组患者接受乌司他丁治疗,对两组患者治疗后的临床疗效进行比较。结果治疗组患者接受乌司他丁治疗后,患者氧合指数、APACHEⅡ评分以及C蛋白反应等指标明显优于对照组患者接受盐水推注治疗,组间经比较,存在的差异显著（P〈0.05）。结论在治疗免疫功能降低并发急性间质性肺炎过程中,选择乌司他丁治疗,其临床效果显著,同时有效改善患者的临床症状。

Objective To investigate the clinical effect of ulinastatin in the treatment of immune function decreased with acute interstitial pneumonia. Methods In our hospital from February 2013 to 2014 June admitted during the period of immune function reduce complicated with interstitial pneumonia in 54 patients, according to the time of admission in patients with will be the group of 54 cases were divided into control group（n = 27） and treatment group（n = 27）, patients in the control group received saline injection therapy, treatment group was treated with ulinastatin treatment, the clinical efficacy of the two groups of patients after treatment compared. Results The treatment group was treated with ulinastatin treatment, patients with oxygen index, APACHE II score and C reactive protein and other indicators is obviously superior to the control group received saline push injection treatment and between groups by comparison, the difference significant（P〈0.05）. Conclusion In the treatment of immune function decreased with acute interstitial pneumonia, choice of ulinastatin treatment. The clinical effect is remarkable, and effectively improve the patient＇s clinical symptoms, it is worth in the clinical application and promotion.