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血小板微粒在心血管疾病中的研究进展 被引量：3

The Research Development of Platelet Microparticle in Cardiovascular Disease
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摘要 血小板微粒是血小板在活化和凋亡过程中产生的一种微颗粒,其膜上表达有多种活性标志物,使其具有重要的生物学活性。血小板微粒不仅具有很强的促凝活性,而且还有一定的抗凝、抗炎及介导细胞间信息传递的作用;其与心血管疾病的发生、发展密切相关,尤其与急性心肌梗死等血栓栓塞性疾病的关系更为密切。随着对血小板微粒认识的不断深入,其有可能成为心血管疾病新的诊疗靶点。 Platelet microparticle is generated with the activation and apoptosis of platelet ,the membrane of which has a variety of active markers,rendering important biological activities.The microparticle not only has strong procoagulating character, but also anticoagulating, anti-inflammatory and mediatiing information transmission between cells.It′s closely related to cardiovascular diseases,especially with acute myocardial infarction and other thromboembolic diseases .With the deepening of understanding of platelet microparticles , it′s expected to become a new diagnostic and therapeutic target for cardiovascular diseases .
作者 梁鹏 周新华 陈开祥
机构地区 蚌埠医学院附属连云港医院 连云港市第二人民医院急诊科
出处 《医学综述》 2015年第13期2340-2343,共4页 Medical Recapitulate
关键词 血小板微粒 心血管疾病 血栓栓塞性疾病 Platelet microparticle Cardiovascular diseases Thromboembolic disease
分类号 R541.4 [医药卫生—心血管疾病]
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参考文献27

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共引文献37

同被引文献38

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引证文献3

二级引证文献9

医学综述
2015年 第13期

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