酮症倾向糖尿病病因及分型研究被引量：2

Pathogenesis and Classification of Ketosis-prone Diabetes

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摘要酮症倾向糖尿病(KPD)是一类以糖尿病酮症酸中毒或自发性酮症起病的糖尿病总称,既包括经典1A型糖尿病、成人隐匿性自身免疫糖尿病、特发性糖尿病,也包括以酮症酸中毒或糖尿病酮症起病的2型糖尿病。多种证据表明KPD是一类异质性疾病,KPD患者在遗传、发病机制、临床表现及β细胞功能储备上均存在差异。KPD合理分型,对研究其病因、发病机制,及血糖接近正常的缓解期治疗方案具有重要意义。 Ketosis-prone diabetes （KPD） is a heterogeneous syndrome characterized by diabetes ketoac-idosis or unprovoked ketosis,which includes classic type 1A diabetes,latent autoimmune diabetes in adults, idiopathic diabetes and type 2 diabetes which with diabetes ketoacidosis or ketosis as onset .There are various of evidences indicating that KPD is a kind of heterogeneous disease,KPD patients have differences in genet-ics,pathogenesis,clinical manifestations,and β-cell function reserves.Reasonable classification of KPD is important to study the etiology,pathogenesis and treatment on near-normoglycemic remission.

作者赵宇洁邓志明

机构地区中南大学湘雅医院内分泌科常德市第一人民医院内分泌科

出处《医学综述》 2015年第13期2409-2411,共3页 Medical Recapitulate

关键词酮症倾向糖尿病病因诊断分型 Ketosis-prone diabetes Pathogenesis Diagnosis Classification

分类号 R587.1 [医药卫生—内分泌]

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