某医院外科住院患者铜绿假单胞菌感染特点与耐药性分析

Analysis of Pseudomonas aeruginosa infection characteristics and resistance of patients in surgical system in a hospital

目的了解外科住院患者铜绿假单胞菌感染特点及其耐药性,为加强防控提供科学依据。方法采用病原微生物分离鉴定技术和药敏试验方法,对某医院外科住院患者感染铜绿假单胞菌临床特点及其耐药性进行观察与分析。结果从该医院外科住院患者送检标本中,共分离出铜绿假单胞菌135株,其中痰标本和创面分泌物标本中分离出菌株构成比居前2位,分别占57.04%和23.70%。感染患者主要分布在神经外科和骨科。临床分离的铜绿假单胞菌对常用抗菌药物普遍耐药,神经外科患者标本分离的菌株耐药率更高。结论该医院临床分离的铜绿假单胞菌,对常用抗菌药物普遍耐药,应针对菌株环境分布加强消毒措施并合理选用抗菌药物。

Objective To understand the Pseudomonas aeruginosa infection in patients with surgical system characteristics and resistance, so as to provide a scientific basis for strengthening the prevention and control. Methods The etiology separation and identification techniques and drug susceptibility test were used to observe and analyze clinical features and drug resistance of Pseudomonas aeruginosa infection in hospitalized patients of surgical system. Results A total of 135 strains Pseudomonas aeruginosa were isolated from samples of the hospital inpatients in surgical system. The strains isolated from sputum specimens and wound secretions ranked the top two, accounting for 57.04% and 23.70 % respectively. The Infected patients were mainly in neurosurgery and orthopedics. Clinical isolates of Pseudomonas aeruginosa were resistant to com- monly used antibiotics in general, and higher drug resistant rate was obtained from strains isolated from the neurosurgical patient specimens. Conclusion The hospital clinical isolates of Pseudomonas aeruginosa are mainly from sputum and wound secretions of patients in neurosurgery and orthopedic department. They are generally resistant to commonly used antimicrobial agents, so disinfection measures and rational use of antimicrobial drugs should be strengthened for the strain distribution environment.