轻度侧脑室增宽胎儿的产前超声诊断和临床评估

Clinical evaluation and ultrasonic diagnosis of mild ventriculomegaly in fetuses

目的评估胎儿轻度侧脑室增宽诊断在临床预后判断中的价值。方法选择2013年1月至2014年6月本院收治的51例侧脑室增宽的孕妇资料,对轻度侧脑室增宽的胎儿进行系统的超声检查、染色体核型分析、MRI检查、随访观察等,最后进行总结分析。结果经彩色多普勒超声诊断侧脑室增宽胎儿共51例,轻度侧脑室26例,其中轻度侧脑室增宽合并其他结构畸形的发生率46.0%(12/26);轻度侧脑室增宽胎儿合并染色体异常发生率为11.5%(3/26)。结论超声对筛查胎儿轻度脑室扩张具有重要诊断价值,对于高龄孕妇及伴发其他结构异常的轻度侧脑室增宽建议行染色体核型分析。

Objective To evaluate the importance of the prenatal diagnosis to fetus with mild ventriculomegaly（ MVM） in pregnancy outcome and prognosis. Methods The ultrosonographic results of 51 pregnant women who were admitted to our hospital were collected in this study. In each case,a thorough evaluation of fetal anatomy was performed,karyotyping or MRI was done if needed,and follow-up was done until afterbirth. Results In 51 cases of lateral ventriculomegaly fetal： ultrasonography indicated there were 26 fetuses with mild ventriculomegaly. The incidence of MVM complicated with other abnormities was 46. 0%,and that complicated with chromosome disorder was 11. 5%. Conclusion Ultrasonography plays an important role in the detection of MVM. Chromosome analysis should be carried out for elder pregnant women when their fetuses are diagnosed as MVM and other complicating abnormities.