摘要
1例83岁男性患者,因干咳6月、呼吸困难4天入院。入院时病情危重,诊断为重症肺炎,不排除放射性肺炎,Ⅰ型呼吸衰竭。联用注射用甲泼尼龙琥珀酸钠和抗真菌药伏立康唑期间,患者出现躁动明显、幻听幻视等谵妄症状。临床药师通过参与患者的药物治疗,探讨合并用药致谵妄的可能机制,为药学监护提出建议。
An 83-year-old male patient was admitted to our emergency department because of dry cough for 6 months and dyspnea for 4 days. He was in a critical condition with diagnoses of severe pneumonia, radioactive pneumonia not excluded, and type I respiratory failure. There appears some neuropsychiatric changes in the patient such as restless, auditory, visual hallucination, and other symptoms of delirium when used prednisolone sodium succinate in combination with Voriconazole, an antifungal drugs. Through the participation in patient＇s medication therapy and literature review, the author discussed the possible mechanisms of drug combination which cause delirium to offer advice for pharmaceutical care.
出处
《药品评价》
CAS
2015年第10期41-44,共4页
Drug Evaluation
