结直肠癌患者血清的紫外光谱研究

The serum ultraviolet spectrum research of colorectal cancer patients

运用紫外光谱技术对21例正常者和56例大肠癌患者血清进行测试与分析,运用SPSS 19.0统计软件分析正常者与结肠癌患者血清中波长为279 nm的吸光度与波长为252 nm的吸光度比值(A279/A252)差异以及与临床各病理指标的关系。结果显示,与正常人血清比较,A279/A252在淋巴结转移组肠癌患者明显增高,在淋巴结未转移组的肠癌患者中明显下降,差异有统计学意义(P<0.05),但其与临床各病理指标如年龄、性别、肿瘤的浸润深度、肿瘤分化等无明显相关性。

By using the ultraviolet spectrum technique, 21 normal controls’ and 56 cases of colorectal cancer pa-tients’ serum were tested and analyzed. Compare the normal controls and colorectal cancer patients’ serum’s ab-sorbance ratio between the wavelength of 279 nm and the wavelength of 252 nm by t-test analysis using SPSS 19. 0. Correlations of the clinical pathological indicators were also analyzed. Compared with the normal serum, A279 / A252 colon cancer patients were significantly higher in the lymph node metastasis group （P 〈 0. 05）, in patients with colorectal cancer lymph node transfer group decreased obviously （P 〈 0. 05）. The correlations between the absor-bance ratio and pathology and clinical indicators such as age, sex, tumor differentiation, tumor infiltration depth were not significant.