多囊卵巢综合征患者体外受精-胚胎移植后的妊娠结局临床研究

Clinical studies of pregnancy outcome of embryo transfer in vitro fertilization patients with polycystic ovary syndrome Z

目的探讨多囊卵巢综合征患者体外受精-胚胎移植后的妊娠结局。方法选取2010年5月至2014年5月收治的多囊卵巢综合征患者50例作为观察组，采用体外受精一胚胎移植治疗，同时选取同期收治的单纯输卵管因素行体外受精-胚胎移植治疗的50例患者为对照组，比较两组患者的妊娠结局。结果观察组妊娠期糖尿病率、妊娠期高血压疾病率、新生儿早产率、剖宫产率均高于对照组，自然分娩率低于对照组，差异均有统计学意义（P〈0．05）。两组足月小于胎龄儿、足月大于胎龄儿、新生儿窒息率比较差异未见统计学意义（P〉0．05）。结论多囊卵巢综合征采用体外受精-胚胎移植治疗，具较高有效性，但妊娠高血压、妊娠糖尿病、流产率、剖宫产率、早产率均较高，需引起临床足够重视。

Objective To investigate the pregnancy outcome of in vitro fertilization-embryo transfer of patients with polycystic ovary syndrome. Methods From May 2010 to May 2014, 50 patients with polycystic ovary syndrome were selected as observation group, they all underwent in vitro fertilization-embryo transfer. At the same time, 50 cases underwent in vitro fertilization-embryo transfer because of simple tubal factor were chosen as control group. The pregnancy outcomes of the two groups were compared.Results The rate of gestational diabetes, hypertensive disorders in pregnancy rate, the rate of preterm neonates, cesarean rates were higher, natural birth rate in the observation group were lower than those in the control group, the differences were significant （P 〈 0.05） . There was no significant difference in the full-term small for gestational age children, fullterm gestational age children or neonatal asphyxia between the two groups （P 〉 0.05）. Conclusions In vitro fertilizationembryo transfer treatment for polycystic ovary syndrome, has higher effectiveness, but the incidences of pregnancy-induced hypertension, gestational diabetes, miscarriage rate, cesarean section rate, preterm birth are high, which should be paid attention to.