三金片与左氧氟沙星在重症急性肾盂肾炎中的临床应用研究

Clinical Research of Sanjin Tablet and Levofloxacin in Severe Acute Pyelonephritis

目的:探讨重症急性肾盂肾炎临床治疗效果。方法:收集2012年2月-2015年2月笔者所在医院收治的70例重症急性肾盂肾炎患者,将患者随机分为两组,均为35例,一组给予患者提供三金片联合左氧氟沙星治疗为研究组;另一组采取氨苄青霉素静脉滴注治疗,为对照组,比两组患者的临床疗效、不良反应发生率及全身症状、局部体征、尿路刺激症状消除等时间。结果:研究组患者治疗总有效率为94.29%,不良反应发生率为8.57%;对照组患者治疗总有效率为74.29%,不良反应发生率为25.71%;研究组患者治疗总有效率明显高于对照组,不良反应发生率明显低于对照组,差异有统计学意义(P<0.05)。研究组患者全身症状、局部体征、尿路刺激症状消除时间明显短于对照组,差异有统计学意义(P<0.05)。结论:三金片合左氧氟沙星治疗重症急性肾盂肾炎,疗效较高,无明显不良反应,患者依从性高,促进患者病情恢复,值得临床推广。

Objective： To research the clinical therapeutic effect of severe acute pyelonephritis.Method： 70 cases with severe acute pyelonephritis from February 2012 to February 2015 were retrospectively analyzed.35 cases were treated with Sanjin Tablet and Levofloxacin as the study group, and another 35 cases with Ampicillin as the control group.Clinical effect, adverse effects, constitutional symptom, and local physical signs, and elimination time of urinary tract stimulus symptoms were recorded and compared.Result： Total effective rate in the study group were 9d.29%, incidence of adverse reactions rate was 8.57%.Total effective rate in the control group were 74.29%, incidence of adverse reactions rate was 25.71%.Total effective rate in the study group was higher, and adverse reaction rates was significantly lower than that in the control group.There were statistically significant difference（P〈0.05）.General symptoms, local physical signs, elimination time of urinary tract stimulus symptoms in the study group were significantly shorter than those in the control group.there were statistically significant difference（P〈0.OS）.Conclusion： The effect of Sanjin Tablet and Levofloxacin together in the treatment of severe acute pyelonephritis is better, with no significant adverse reactions and can promote patient recovery .This treatment is worthy of promotion.