婴幼儿喘息166例临床分析

Analysis on 166 Infants with Wheezing

目的:探讨婴幼儿喘息的临床特征。方法:选取2012年11月-2014年5月住院喘息患儿共166例,其中反复喘息58例(喘息组),毛细支气管41例(毛细支气管炎组),肺炎67例(肺炎组),并于入院当天及第7天行外周血血常规检查。入院次日行呼吸道病原Ig M、肺炎支原体、Ig E、过敏原等检测。结果:喘息组、毛细支气管炎组的嗜酸性粒细胞、Ig E高于肺炎组,差异有统计学意义(P<0.05),其中喘息组Ig E及嗜酸性粒细胞最高。喘息组、毛细支气管炎组湿疹史及过敏史比率比肺炎组高,差异有统计学意义(P<0.05)。结论:婴幼儿喘息性疾病与过敏因素密切相关。

Objective： To investigate the clinical features of wheezing in infants.Method： 166 infants with wheezing from November 2012 to May 2014 in our hospital were selected, 58 cases with recurrent wheezing diagnosed as asthma group, 41 cases with bronchiolitis in brotlchiolitis groups and 67 cases with pneumonia in pneumonia groups.The peripheral blood routine examination on 1 d and 7 d were analyzed.The pathogenic IgM and Mycoplasma pneumoniae, IgE and allergen analysis were performed in hospital admission next day.Result： IgE and EOS count in the recurrent wheezing group and the bronchiolitis group were higher than that in the pneumonia group with significant difference（P〈O.05）.The recurrent wheezing group was highest in IgE and EOS count among three groups.The prevalence of allergic and eczema history in recurrent wheezing group and bronchiolitis group were higher than pneumonia group with significant difference（P〈0.05）. Conclusion： Wheezing in infants is related with allergic factors.