雾化吸入治疗婴幼儿哮喘急性发作临床疗效及C反应蛋白水平观察

The Clinical Efficacy of Inhalation in the Treatment of Infants with Acute Asthma and Observation of C Reactive Protein Levels

目的:探讨雾化吸入治疗婴幼儿哮喘急性发作的临床疗效及C反应蛋白水平变化。方法:将120例婴幼儿哮喘急性发作患儿分为两组,对照组采用常规治疗,观察组联合雾化吸入治疗。结果:治疗4、7 d后观察组夜间哮喘评分高于对照组。观察组喘憋缓解、咳嗽消失、肺部体征消失、平均住院时间明显低于对照组(P<0.05)。观察组治疗后外周血WBC计数及血清hs-CRP水平低于治疗前(P<0.01),Sa O2高于治疗前(P<0.01)。结论:雾化吸入治疗效果理想,可显著提高Sa O2,血清hs-CRP定量检查可作为病情观察及指导治疗的一项指标。

Objective： To investigate the clinical efficacy of inhalation in the treatment of infants with acute asthma and the change of C-reactive protein（CRP） levels.Method： 120 cases with acute exacerbation of asthmatic children were divided into two groups, the control group was taken conventional therapy, the observation group was combined with inhalation therapy.Result： The nocturnal asthma score after 4 days, 7 days in the observation group was higher than that in the control group（P〈0.05）.Whcezing ease, cough disappeared, pulmonary symptoms disappear, the average hospital stay in the observation group were significantly lower than those in the control group（P〈0.05）.Peripheral WBC count and serum hs-CRP levels after treatment were lower than before treatment in the observation group（P〈0.01）, SaO2 was higher than before treatment（P〈0.01）.Conelusion： The therapeutic effect of inhalation is well, it can significantly improve the Sa02, quantitative examination of serum hs-CRP can be used as an indicator of the condition of observation and to guide treatment.