摘要
目的探讨血脂异常对系统性红斑狼疮患者的意义。方法选取系统性红斑狼疮患者124例,按血脂水平有无异常将患者分别设为观察组84例和对照组40例。观察2组总胆固醇(Tc)、甘油三酯(T)、高密度脂蛋白胆固醇(HDL-)、低密度脂蛋白胆固醇(LDL—L)水平,补体c3、c4水平,血沉速度,肾病、血液病变、抗核酸抗原抗体(ANA)阳性的发生情况。结果观察组患者TC、TG、LDL-L水平高于对照组,HDL-L水平低于对照组,差异均有统计学意义(P〈0.01)。观察组肾病、血液病变、ANA阳性发生率高于对照组,差异有统计学意义(P〈0.01)。观察组补体c3、c4水平低于对照组,观察组血沉速度高于对照组,差异有统计学意义(P〈0.01)。结论系统性红斑狼疮患者血脂异常作为临床参考指标,具有一定的参考价值。
Objective To investigate the correlation between systemic lupus erythematosus patients with dyslipidemia. Methods A total of 124 patients with systemic lupus erythematosus were assigned to observation group (n = 84, with dyslipidemia) and control group (n =40, without dyslipi- demia). The total cholesterol (TC), triglyceride (TG), high density lipoprotein cholesterol (HDL- L), Low density lipoprotein cholesterol (LDL-L), complement C3and C4, sedimentation rate were observation , as well as incidence of nephropathy, hemopathy and nucleic acid resistant antigen anti- body (ANA) positive. Results The observation group had higher levels of TC ,TG, LDL-L and lower HDL-L compared with the control group (P 〈 0.01 ). The incidence of nephropathy, hemopathy and ANA positive were higher in observation group than that in control group (P 〈 0.01 ). the observation group had a lower level of complement C3and C4, but higher sedimentation rate compared with the control group (P 〈 0.01 ). Conclusion Dyslipidemia may be useful for as an indicator in systemic lupus erythematosus patients.
出处
《实用临床医药杂志》
CAS
2015年第E01期62-63,共2页
Journal of Clinical Medicine in Practice
关键词
系统性红斑狼疮
血脂异常
危险因素
抗核酸抗原抗体
systemic lupus erythematosus
dyslipidemia
risk factors
nucleic acid resistant antigen antibody