老年血液透析患者BNP水平变化及其评估干体重的意义

Changes of BNP level of elderly patients undergoing hemodialysis and its significance in the assessment of dry weight

目的：探讨老年血液透析病人BNP水平变化及其评估患者干体重的意义。方法：统计分析我院2013年1月至2014年9月收治的46例老年血液透析患者的临床资料。结果：研究组患者下调体重后的血浆BNP浓度、CTR、体重均显著低于下调体重前（P〈001），但和对照组人员的血浆BNP浓度、CTR、体重之间的差异均不显著（P〉0．05）；研究组患者下调体重前后血浆BNP浓度之差和CTR、体重之差均显著相关（P〈O．05）；研究组患者下调体重后的轻度气促、胸闷，恶。腹部饱胀，明显面部或下肢浮肿，高血压症状发生率均显著低于下调体重前（P〈0．05）。结论：老年血液透析病人BNP水平变化能够评估患者干体重，值得在临床推广。

Objective To investigate the changes of BNP level of elderly patients undergoing hemodialysis and its significance in the assessment of dry weight. Methods the clini- cal data of 46 cases of elderly hemodialysis patients who were treated in our hospital from January 2013.to September 2014 were statistically analyzed. Results The plasma BNP concen- tration , CTR, body weight after weight reduction of the study group was significandy lower than before weight reduction （ P 〈 0.01 ）, but the differences of BNP level personnel, CTR, body weight between the control group and it were not significant （ P 〉 0. 05 ） ; the differences between plasma BNP concentrations difference and CTR, body weight differences before and after reducing body weight of the study group were significantly associated （P 〈0. 05 ） ; The inccidence of slightly breath, chest tightness, nausea, abdominal fullness, obviously the face or lower extremity edema, hypertension symptoms after shortness of body weight of the study group were significantly iower than before the weight down （ P 〈 0. 05 ）. Conclusion Changes of BNP level can assess the dry weight of elderly patients undergoing hemodialysis, so is worthy of promotion in the clinical.