熟三七配方颗粒的质量分析研究

Study on Quality Standard of Steamed Notoginseng Formula Granules

目的:进行熟三七配方颗粒的质量标准研究,建立质量评价方法,为科学评价其质量提供依据。方法:采用薄层色谱法(TLC)对熟三七配方颗粒中人参皂苷Rh1、Rg3进行鉴别,采用高效液相色谱法(HPLC)对其三七皂苷R1,人参皂苷Rg1、Re、Rb1、Rd进行含量检测分析。结果:建立了熟三七配方颗粒中人参皂苷Rh1、Rg3的薄层鉴别方法;建立了检测熟三七配方颗粒中三七皂苷R1,人参皂苷Rg1、Re、Rb1、Rd的含量测定方法。结论:该方法简单、准确、专属性好,能有效对熟三七配方颗粒的质量进行评价。

Objective： To establish the quality standard for steamed Notoginseng formula granules, and provide a basis for scientific evaluation of its quality. Methods： Ginsenosides RhI and ginsenoside Rg3 in steamed Notoginseng formula granules were identified by TLC, and the contents of notoginsenoside R1, ginsenosides Rg, Re, Rb1 , Rd in steamed Notoginseng formula granules were determined by HPLC. Results： To established a method to identify Panax ginseng saponin Rh1 and ginsenoside Rg3 in Steamed Notoginseng Formula Granules by TLC ; to establish a method to detect the content of Panax notoginsenoside R1, ginsenosides Rg1, Re, Rbl, Rd in Steamed Formula Notoginseng Granules. Conclusion： The established method is simple, accurate, reproducible, and it can be used as a quality control method for steamed Notoginseng formula granules.