养阴柔肝化湿解毒方治疗慢性乙型肝炎随机平行对照研究

Parallel Randomized Controlled Study of Chronic Hepatitis B and Yin Rougan Dampness Detoxification Treatment

[目的]观察养阴柔肝化湿解毒方治疗慢性乙型肝炎疗效。[方法]使用随机平行对照方法,将200例门诊患者按掷骰子法简单随机分为两组。对照组100例澳泰乐,15g/次,3次/d。治疗组100例养阴柔肝化湿解毒方(生地、白芍、虎杖、车前子、茵陈、半枝莲、川石斛、沙参各15g,苦参、苍术各9g,丹参、猫人参、马鞭草、岗稔根各30g,生甘草6g;神疲乏力严重加黄芪炙、党参各15g;胀满严重加青皮、柴胡、生枳壳各9g),1剂/d,水煎400m L,早晚口服。连续治疗30d为1疗程。观测临床症状、ALT、AST、ALB、TBIL、不良反应。连续治疗3疗程,判定疗效。[结果]治疗组显效67例,有效29例,无效4例,痊愈率67.00%。对照组显效41例,有效49例,无效10例,痊愈率41.00%。治疗组疗效优于对照组(P<0.01)。肝功能指标两组均有改善(P<0.01),治疗组改善优于对照组(P<0.01)。[结论]养阴柔肝化湿解毒方治疗慢性乙型肝炎效果显著,值得推广。

[Objective] To observe Yangyin Rougan dampness detoxification treatment of chronic hepatitis B side. [Methods]Using random parallel control method, 200 cases of outpatients by the dice method is simple randomized into two groups. The control group 100 cases Macao and Thailand music, 15 g / time, 3 times/d. Softening treatment group 100 cases Yangyin dampness detoxification side（Shengdi,Baishao,Huzhang,Cheqia nzi,Yinchen,Banzhilian,Chuanshihu, Shashen 15 g, Kushen,Cangzhu 9g, Danshen,Maorenshen,Mabiancao 30 g, Gancao 6g; lassitude serious Sunburn Huangqi,DAngshen 15g; fullness serious plus Qingpi,Chaihu,Shengzhike 9g）, 1/d, decoction 400 m L, Sooner or later orally. 30 d is a continuous course of treatment. Observation of clinical symptoms, ALT, AST, ALB, TBi L, adverse reactions. Continuous treatment for 3 courses, to determine efficacy. [Results] treatment group 67 cases, effective 29 cases, 4 cases, recovery rate 67.00%. Control group, 41 cases markedly effective in 49 cases, 10 cases, 41.00% cure rate. Treatment group than the control group（P〈0.01）.Liver function were improved in both groups（P〈0.01）, improvement in the treatment group than the control group（P〈0.01）. [Conclusion] Yin Rougan dampness detoxification treatment of chronic hepatitis B side effect is significant, it is worth promoting.