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通脉降浊汤与西药对急性冠脉综合征介入后生命质量影响等效性随机平行对照研究 被引量:3

Study on the Effects of Tongmaijiangzhuofang on Quality of Life in Treating ACS Patients after PCI
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摘要 [目的]观察通脉降浊汤对急性冠脉综合征介入后生命质量影响。[方法]使用随机平行对照方法,将62例住院患者按病志号抽签方法简单随机分为两组。对照组31例阿司匹林、低分子肝素、单硝酸异山梨酯、他汀类药物等抗血小板聚集、抗凝、改善心脏供血、降脂及稳定斑块等综合性对症治疗。治疗组31例通脉降浊汤(大黄10g,枳实、柴胡、黄芩各15g,清半夏10g,丹参、白芍、茯苓、陈皮各20g,甘草10g),1剂/d,水煎300m L,早晚口服。连续治疗14d为1疗程。观测临床症状、生命质量、不良反应。治疗1疗程,判定疗效。[结果]治疗组显效22例,有效8例,无效1例,总有效率96.80%。对照组显效15例,有效13例,无效3例,总有效率90.30%。两组间无明显差异(P>0.05)。躯体功能(PF)、一般健康(GH)、心理健康(MH)治疗组均优于对照组(P<0.05)。[结论]通脉降浊汤治疗急性冠脉综合征介入后,疗效满意,无严重不良反应,值得推广。 [Objective] To explore the health status and quality of life of ACS patients after PCI treating by Tongrnaijiangzhuofang. [Methods] 62 ACS patients after PCI were randomly divided into treatment group and control group with 31 cases in each. The control group was treated with aspirin, Low molecular weight heparin, isosorbide mononitrate, statins to anticoagulant, anti platelet aggregation, improve the blood supply of the heart, reduce blood lipids, stabilize plaque and other comprehensive treatment. The treatment group was treated by Tongmaijiangzhuofang(Dahuang 10g, Zhishi, Chaihu and Huangqin each 15g, Qingbanxia 10g, Danshen, Baishao, Fuling, Chenpi each 20g, Gancao 10g) 1 agent/d, 300mL oral water decoction, two dose in the rooting and night. 14d continuous treatment was 1 course of treatment. The clinical symptoms, quality of life and adverse reaction were observed. Treatment efficacy was determined after 1 course of treatment. [Results] In the treatment group, 22 cases were markedly effective, 8 cases effective, and 1 cases invalid, the total efficiency of 96.80%. The control group 15 cases markedly effective, effective 13 cases, invalid 3 cases, the total efficiency of 90.30%. No significant difference between the two groups (P〉0.05). Physical function (PF), general health (GH), mental health (MH) of treatment group were superior to the control group (P〈0.05). [Conclusion] Effect of Tongmaijiangzhuofang in treating acute coronary syndrome after PCI is satisfied, no serious adverse reactions, and it can improve the long-term quality of life and is worthy of promotion.
作者 王乐 王凤荣
出处 《实用中医内科杂志》 2015年第7期107-109,共3页 Journal of Practical Traditional Chinese Internal Medicine
关键词 急性冠脉综合征 胸痹心痛 介入性治疗 生命质量 SF-36慢性病生命质量量表 中医药治疗 等效性随机平行对照研究 acute coronary syndromes chest pain PCI quality of life SF-36 quality of life scale for chronic disease Treatment of traditional chinese medicine study on equivalence of random parallel control
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