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难治性终末期心衰45例临床分析 被引量:3

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摘要 目的:探讨难治性终末期心衰患者较为理想的治疗方法及效果。方法:将难治性终末期心衰45例患者随机分成行强化利尿治疗(强化利尿组)21例,连续性静脉血液滤过(血滤治疗组)24例,2组患者均使用血管活性药,必要时静滴白蛋白、血浆维持血压于95-100 mm Hg。结果:血滤治疗组患者短期疗效明显好于强化利尿组患者,强化利尿组21例中显效4例(19.0%),有效13例(61.9%),无效4例(19.0%);血滤治疗组24例中显效18例(75.0%),有效6例(25.0%)。两组总有效率比较差异有统计学意义(Z=3.873,P〈0.05)。强化利尿组平均重症监护病房时间11.5±8.6天,平均住院时间28.2±14.8天,4周死亡4例,心衰复发11例次,1年死亡6例,心衰复发43例次;血滤治疗组平均重症监护病房时间6.4±3.7天,平均住院时间17.6±10.5天,4周死亡0例,心衰复发4例次,1年死亡8例,心衰复发36例次。强化利尿组患者住ICU时间及平均住院时间明显长于血滤治疗组患者(P〈0.05),2种方法对患者的短期预后明显不同(P〈0.05),但随访1年2组患者心衰复发率无明显差异(P〉0.05)。结论:难治性终末期心衰患者应尽早行连续性静脉血液滤过治疗,能明显改善这类患者生存率并相应提高其生活质量。
作者 邱祖红 季勇
出处 《交通医学》 2015年第3期261-263,265,共4页 Medical Journal of Communications
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参考文献9

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二级参考文献23

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