全视网膜激光光凝对糖尿病患者视网膜与角膜的影响

Influence of pan retinal photocoagulation on diabetic retinal and corneal

糖尿病视网膜病变是糖尿病最严重的微血管并发症之一,也是一种世界性的主要致盲眼病。虽然眼内注射抗血管内皮生长因子药物正成为当前治疗的研究热点,但全视网膜激光光凝仍然是目前治疗DR的最有效、普遍、经济的方法之一。作为一种破坏性治疗手段,全视网膜激光光凝必然会对视网膜和角膜的正常结构形态和功能造成一定的影响。随着光学相干断层扫描、共聚焦显微镜等辅助检查技术的不断发展,准确客观的研究这些结构变化,有助于我们改良光凝方法,减少光凝副作用以最大限度的保护患者的视功能。

Diabetic retinopathy（DR） is one of the most serious microvascular complications of diabetes.It also is a world＇s major causes of blind eye diseases.Although the injection of anti- vascular endothelial growth factor intraocular drug is becoming a hotspot of current research.Pan retinal photocoagulation（PRP） remains the effective and economical treatment for DR.As a destructive treatment,PRP will inevitably cause some changes on the normal morphology and function of the retinal and cornea.Currently,with the development of the optical coherence tomography,confocal microscopy and other auxiliary examination,we have more accurate and objective research to better understand the laser-neural tissue interaction.This may help us to protect the patient＇s visual function more efficiently.