暗适应3.0振荡电位对视网膜中央静脉阻塞的临床应用

Clinical research of dark adaptation 3.0 oxillatory potentials in central retinal vein occlusion

目的:探讨暗适应3.0振荡电位对视网膜中央静脉阻塞的临床应用价值。方法:视网膜中央静脉阻塞患者84例84眼,初诊时行振荡电位检查,依据本实验室正常值进行分组,无波型(16例),重度降低型(27例),中度降低型(20例),轻度降低型(21例)。无波型与重度降低型拟诊缺血型视网膜中央静脉阻塞。轻度降低型与中度降低型拟诊非缺血型视网膜中央静脉阻塞。随访6mo,记录对比检查结果,共76例资料完整(8例失访)。结果:重度降低型与无波型共34例(83%),最终诊断为缺血型视网膜中央静脉阻塞,中度降低型5例(25%)、轻度降低型0例最终诊断为缺血型视网膜中央静脉阻塞,三组比较具有统计学差异(χ2=34.5,P<0.01),其中重度降低型与轻度降低型以及中度降低型比较,具有统计学差异(P<0.01),轻度降低型与中度降低型比较,无统计学差异(P=0.036)。结论:视网膜中央静脉阻塞早期的振荡电位振幅降低,振荡电位对视网膜中央静脉阻塞早期分型和预后评估有重要意义。

AIM：To investigate the clinical value of dark adaptation3.0 oscillatory potentials in central retinal vein occlusion.METHODS：Eighty-four patients（84 eyes） with central retinal vein occlusion were divided into 4 groups：no wave type（16 cases）,grossly decreased type（27 cases）,middle decreased type（20 cases） and slightly decreased type（21 cases） accorded to the normal value of this experiment.The initial diagnosis was the examination of oscillatory potentials.No wave and grossly decreased type were first diagnosed as ischemic central retinal vein occlusion,middle and slightly decreased type were first diagnosed as non- ischemic central retinal vein occlusion.The patients were followed up for 6mo,recorded and contrasted the examination results between anterior and posterior.There were 76 cases having integrated data（8 cases were lost）.RESULTS：No wave and grossly decreased type were ultimately diagnosed as ischemic central retinal vein occlusion（34 cases,83%）,middle decreased type（5cases,25%） and slightly decreased type（0 case）.There was statistically significant difference between the three groups（χ^2 =34.5,P〈0.01）.The statistical difference still existed comparing the grossly decreased type and the middle decreased type with slightly decreased type（P〈0.01）.However,there was no significant difference between the middle and slightly decreased type（P=0.036）.CONCLUSION：The early oscillatory potential amplitudes of central retinal vein occlusion is decreased,which has important significance for early classification and prognosis of central retinal vein occlusion.