3～14岁矮小症患儿的病因研究

Etiological analysis of dwarfism in children aged 3 ～ 14

目的分析3~14岁矮小儿童的病因,为该类患儿的诊断提供依据。方法回顾性分析徐州医学院附属医院儿科医院内分泌科3年内收治的198例矮小症患儿的病史、体格检查、相关实验室检查。结果本组病例中导致患儿生长迟缓的病因有14种,主要病因有生长激素缺乏症（GHD）75例（37.88%）,特发性矮身材（ISS）43例（21.72%）,青春发育延迟（CDGP）20例（10.10%）,性早熟（SP）13例（6.56%）。结论导致生长迟缓的病因繁多,以GHD、ISS、CDGP最为常见。

Objective To investigate and analyze the dwarf reasons for children among 3 ~ 14 years old. Methods Retrospectively analyzed the data of 198 cases of children with short stature in the affiliated hospital of Xuzhou medical col- lege,including pathography,physical and laboratory tests results. Results GHD was the most common disease among the 198 children. There were 75 case （37.88%） diagnosed as growth hormone deficiency （GHD） ;43 cases （21.72%） idiopathic short stature（ISS） ;20 cases （ 10.10% ） constitutional delay of growth and puberty（ CDGP）, 13 cases （6.56%） Sexual pre- cocity（SP）. Conclusion The causes of short stature are complicated . GHD, ISS, SP are the common cause among them.