孟鲁司特钠联合布地奈德治疗小儿咳嗽变异性哮喘的效果观察

Effect observation of montelukast sodium combined with budesonide in the treatment of pediatric cough variant asthma

目的 探讨孟鲁司特钠联合布地奈德治疗小儿咳嗽变异性哮喘的临床效果。方法 将2012年1月-2014年1月汕头市澄海区人民医院儿科收治确诊的68例小儿咳嗽变异性哮喘患儿随机分为治疗组和对照组,各34例。对照组主要采用布地奈德治疗,治疗组采用孟鲁司特钠联合布地奈德治疗,比较两组患儿的相关临床指标和临床效果。结果 治疗组的总有效率为97.06%,明显高于对照组的79.41%,咳嗽缓解、消失时间,治疗时间明显短于对照组（P〈0.05）。结论 孟鲁司特钠联合布地奈德雾化吸入治疗小儿咳嗽变异性哮喘的临床效果明显,值得临床推广应用。

Objective To explore the clinical effect of montelukast sodium combined with budesonide in the treatment of pediatric cough variant asthma. Methods From January 2012 to January 2014,68 pediatric patients with cough variant asthma diagnosed and admitted into our department of pediatrics in People＇s Hospital in Chenghai District of Shantou City were evenly divided into treatment group and control group in random.In control group,budesonide as a main therapeutic method was applied,while in treatment group,montelukast sodium combined with budesonide was pro- vided.The related clinical indicator and clinical effect of patients between two groups was compared respectively. Re- sults The total effective rate in treatment group （97.06%） was obviously higher than that in control group （79.41%）.Time of mitigation and disappearance for cough and treatment time in treatment group was shorter than that in control group respectively （P〈0.05）. Conclusion Montelukast sodium combined with budesonide for aerosol inhalation treating pediatric cough variant asthma can obtain a remarkable effect,which is worthy of promotion and application in clinic.