中西医结合治疗乳腺癌术后化疗所致骨质疏松的效果分析

Effect analysis of integrated traditional Chinese and western medicine treating osteoporosis caused by chemotherapy after breast cancer surgery

目的 探讨中西医结合治疗乳腺癌术后化疗所致骨质疏松的临床效果。方法 选取本院2013年7月-2014年1月收治的68例乳腺癌术后化疗所致骨质疏松患者,随机将其分为观察组和对照组,每组34例。观察组给予中西医结合治疗,对照组给予常规西医治疗。比较两组的疗效、治疗前后不同部位骨密度及血钙水平变化情况。结果 观察组的总有效率为94.1%,对照组为73.5%,两组比较,差异有统计学意义（P〈0.05）。两组治疗1年后的腰椎和股骨颈骨密度均增加,血钙水平上升,与治疗前比较差异有统计学意义,同时两组间差异有统计学意义（P〈0.05）。结论 中西医结合治疗乳腺癌术后化疗所致骨质疏松的临床效果显著,能够明显改善患者的临床症状,调节其骨代谢,从而起到标本兼治的作用。

Objective To explore the clinical effect of integrated traditional Chinese and western medicine treating osteoporosis caused by chemotherapy after breast cancer surgery. Methods From July 2013 to January 2014,68 patients with osteoporosis caused by chemotherapy after breast cancer surgery in our hospital were selected and evenly divided into observation group and control group in rand0m.In observation group,integrated traditional Chinese and western medicine treatment was applied,while in control group,conventional western medicine treatment was provided.The clini- cal effect,bone mineral density （BMD） in different position,and change of serum calcium level before and after treatment between two groups was compared respectively. Results The total effective rate in observation group was 94.1%,while in control group,the rate was 73.5% ,and there was a statistical difference between two groups （P〈0.05）.BMD of lumbar vertebra and neck of femur after 1 year treatment was increased respectively,serum calcium level was improved in two groups,and there was a statistical difference compared with before treatment,and there was a statistical difference between two groups （P〈0.05）. Conclusion Integrated traditional Chinese and western medicine treating osteoporosis caused by chemotherapy after breast cancer surgery can obtain a remarkable clinical effect,and can obviously improve clinical symptoms and regulate bone metabolism of patients so as to play the role of treating both manifestation and root cause of disease.