围绝经期综合征患者性激素水平与体质学说阴虚质、气郁质关系研究

A study on the relationship between the sex hormones levels in perimenopausal Syndrome and Yin-deficiency and Qi-stagnancy of Physique Theory

目的:研究中医体质学说中阴虚质和气郁质围绝经期综合征患者的性激素水平。方法:纳入围绝经期综合征患者,阴虚质和气郁质各30例。对两组患者外周血雌二醇(E2)、促黄体生成素(LH)、催乳素(PRL)、促卵泡生成激素(FSH)水平进行测定对比。结果:两组患者的LH、PRL水平对比并无显著差异(P>0.05),阴虚质患者的FSH水平显著高于气郁质患者,而E2水平则明显低于气郁质患者,差异均具有统计学意义(P<0.05)。结论:围绝经期综合征患者的体质特征对卵巢储备功能存在影响,阴虚质患者的卵巢储备功能普遍低于气郁质患者,提示中医体质学说能够为围绝经期综合征患者的早期干预提供指导。

Objective：To study the sex hormones levels of Yin-deficiency and Qi-stagnancy constitution under the theory of TCM physique in the pa tients with Perimenopausal s yndrome（PMS）. M ethods：S elect60 p atients of P MS ,divide into 2 grou ps equally b y Yin-deficiency and Qi-stagnancy.Measure the levels of Estradiol （E2）, luteinizing hormone （LH）, Prolactin （PRL） and follicular-stimulating hormone （FSH）. Results：No significantdifference in LH and PRL between the two groups;the level of FSH of Yin-deficiency was higher than thatof Qi-stagnancy ;the E2 l evel of Y in-deficiency was l ower than thatof Qi-stagnancy , and both are statistically s ignificant（P〈0.05）.Conclusion：The constitutional feature of patients with PMS has an impacton ovarian reserve function, the Yin-deficiency is commonly lower than thatof Qi-stagnancy. This provides clues thatthe theory of TCM physique can be the guidelines of early intervention for patients with PMS.