介孔碳/纳米金修饰电极同时测定多巴胺、抗坏血酸和尿酸

Simultaneous Determination of Dopamine,Ascorbic Acid and Uric Acid by Mesoporous Carbon/Gold Nanoparticle Modified Electrode

采用溶胶法制备了介孔碳/纳米金复合材料,并利用透射电子显微镜、扫描电子显微镜和X射线衍射仪进行了表征。将合成的复合材料修饰于玻碳电极表面,用循环伏安法同时测定多巴胺（DA）、抗坏血酸（AA）和尿酸（UA）。在pH 7.2磷酸盐缓冲溶液中,DA、AA和UA的氧化峰得到了很好的分离;和裸电极比,介孔碳/纳米金修饰电极对DA、AA和UA具有良好的电催化作用,DA、AA和UA的氧化峰的峰电流强度分别增加1.7,2.0,12倍,3种物质的浓度分别在0.20-45.8,4.0-792.0,0.06-166.0μmol·L-1范围内与其峰电流强度呈线性关系,检出限（3S/N）分别为0.075,7.5,0.021μmol·L^-1。

Au nanoparticles were loaded onto the ordered mesoporous carbon CMK-3by a sol-gel method.The obtained composites were characterized by TEM,SEM and XRD.The Au/CMK-3 modified glassy carbon electrode（GCE）was used to simultaneously detect dopamine（DA）,ascorbic acid（AA）and uric acid（UA）by cyclic voltammetry.In a PBS buffer solution（pH=7.2）,the oxidation peaks of AA,DA and UA were well separated from each other.The Au/CMK-3modified electrode displayed excellent electrochemical catalytic activities for DA,AA and UA.The intensity of the oxidation peak currents of DA、AA and UA on Au/CMK-3 modified electrode was increased by 1.7,2,12 times,respectively,comparing with bare electrode.Linear relationship was found between the intensity of oxidation peak current of DA,AA and UA with the concentration in the range of0.20-45.8,4.0-792.0,0.06-166.0μmol·L^-1 and the detection limits were 0.075,7.5,0.021μmol·L^-1,respectively.