摘要
目的:观察中晚期食管癌患者外科手术前新辅助放化疗的临床护理疗效。方法:试验组136例患者在放疗基础上术前采用2个周期的顺铂加氟尿嘧啶的化疗方案,化疗后2周手术;对照组136例患者无化疗行直接手术。结果:试验组肿瘤明显缩小,其中根治性切除112例,占82.35%;对照组根治性切除89例,占65.44%。两组对比差异显著(P<0.01)。结论:术前新辅助放化疗可降低食管癌肿瘤分期,提高根治性切除手术率,提高术后生存率及生存质量。
Objective：To observe the clinical changes of local advanced esophageal carcinoma treated with new adjuvant chemotherapy before operation and subsistence rate of ostoperation.Methods：136 cases with esophageal carcinoma take two periodic chemotherapy before operation. The other 136 cases take operation directly.Results：In the test group,the lengths of lesions for 116 cases reduced,and112 cases were resected entirely（85.35%）. In the other group,89 cases were resected entirely（65.44%）. There were significant differences between the two groups（P0.01）.Conclusion：New adjuvant chemotherapy could debase the stage of esophageal carcinoma,increase the resection rate and subsistence rate.
出处
《北方药学》
2015年第8期180-181,共2页
Journal of North Pharmacy
关键词
中晚期食管癌
新辅助放化疗
手术
生存率
Esophageal carcinoma New adjuvant chemotherapy Operation Subsistence rate
