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含莫西沙星的超短程化疗方案治疗初治菌阳肺结核的临床观察 被引量:11

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摘要 目的探讨含莫西沙星的超短程化疗方案治疗初治菌阳肺结核的临床疗效。方法将72例初治菌阳肺结核患者按照化疗方案分为对照组35例与观察组37例,对照组采用2HRZE/4HR化疗方案,观察组采用含莫西沙星的2HRZEM/2HRM超短程化疗方案比较两组治疗2个月内痰菌阴转情况、病灶吸收情况、治疗前后SF-12生活量表评分情况及不良反应发生情况。结果经治疗,观察组患者治疗后1个月及2个月痰菌阴转率均显著高于对照组(P<0.05);观察组病灶吸收总有效率显著高于对照组;两组治疗后SF-12各维度(躯体功能、躯体角色、肌体疼痛、总的健康状况、活力、社会功能、情绪角色、心理卫生)评分均显著高于治疗前(P<0.05,P<0.01),且观察组治疗后上述评分均显著高于对照组治疗预后(P<0.05)。结论含莫西沙星的超短程化疗方案治疗初治菌阳肺结核的临床疗效显著,生活质量显著提高。
出处 《海峡药学》 2015年第6期105-106,共2页 Strait Pharmaceutical Journal
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