先兆子痫肾损害发病机制的研究进展

Advances in the pathogenesis of renal involvement in pre-eclampsia

先兆子痫肾损害确切发病机制尚不清楚,多数文献认为胎盘滋养层细胞侵入、免疫系统异常等是先兆子痫肾损害的主要因素。近年来,随着分子生物学的进展,先兆子痫肾损害发病机制研究取得了长足的进展。因而,本文结合文献对先兆子痫肾损害发病机制的进展进行综述。

The exact pathogenesis of renal involvement in pre-eclampsia is unclear. The majority of the literature suggests that placental trophoblast invasion, immune system abnormalities are major factors of renal involvement in pre-eclampsia. In recent years, with the advances in molecular biology, the pathogenesisa of renal involvement in pre-eclampsia has made considerable progress. This paper reviewed the progress on pathogenesis of renal involvement in pre-eclampsia.