醉鱼草果实黄酮类化学成分研究

Study on Flavonoids in Buddleja lindleyana Fruits

目的：研究醉鱼草果实黄酮类化学成分。方法：利用硅胶、RP-18、SephadexLH-20等柱色谱手段进行分离,根据理化性质和波谱分析鉴定化合物结构。结果：从醉鱼草果实中分离得到5个黄酮类化合物,分别鉴定为：木犀草素（1）、小麦黄素（2）、金合欢素（3）、金合欢素-7-O-β-D-葡萄糖苷（4）、蒙花苷（5）。结论：其中,化合物2为首次从该属植物中分离得到,化合物3~5为首次从醉鱼草果实中分离得到。

Objective： To study the flavonoids in the fruits of Buddleja lindleyana. Methods： The compounds were separated by repeated silica gel,RP-18 and Sephadex LH-20. Their structures were elucidated on the basis of chemical evidence and spectral data. Results： Five flavonoids were isolated and identified as luteolin（ 1）,tricin（ 2）,acacetin（ 3）,acacetin-7-O-β-D-glucopyranoside（ 4） and linarin（ 5）. Conclusion： Compounds 3,4 and 5 are isolated from fruits of Buddleja lindleyana for the first time. Compound 2 is isolated from fruits of Buddleja lindleyana for the first time.