腹型肥胖对高血压患者血压变异性的影响

Effect of abdominal obesity on blood pressure variability in patients with hypertension

目的评估腹型肥胖对原发性高血压患者血压变异性的影响。方法选择2014年1月至2014年4月核工业416医院收治的单纯性高血压患者159例,根据患者腹围分组,腹围正常者(男性<90 cm,女性<85 cm)72例为对照组,其中男38例,女34例;合并腹围增高者(男性≥90 cm,女性≥85 cm)87例为观察组,其中男45例,女42例。所有患者行24 h动态血压监测(ABPM),观察患者血压变异性(BPV)的特点。结果观察组24 h收缩压变异系数、日间平均收缩压变异系数均高于对照组,差异有统计学意义(P<0.05);两组男性患者夜间平均舒张压变异系数均高于女性患者,差异有统计学意义(P<0.05);且观察组男性患者24 h收缩压变异系数高于女性患者,差异有统计学意义(P<0.05)。结论腹型肥胖时,高血压患者BPV增高,且男性患者较女性患者明显。

Objective To investigate the effect of abdominal obesity on blood pressure variability（ BPV） in patients with primary hypertension. Methods A total of 159 patients who were admitted to nuclear industry 416 hospital because of simple hypertension were enrolled in this study and divided into two groups based on waist circumference（ WC）. Patients with normal WC（ male 90 cm,female 85 cm,n = 72） as the control group and patients with high WC（ male≥90 cm,female≥85 cm,n = 87）as the observation group. The characteristics of their BPV were observed respectively through 24-hour ambulatory blood pressure monitoring（ ABPM）. Results The CV of both the 24-hour systolic blood pressure and the daytime average systolic blood pressure of patients of observation group were higher than those of control group,and the differences were statistically significant（ P〈0. 05）. The CV of nighttime average diastolic blood pressure of male patients of the two groups were higher than those of female patients of the two groups,and the differences were statistically significant（ P〈0. 05）; In the observation group,the CV of 24-hour systolic blood pressure of male patients were higher than those of the female patients,and the differences were statistically significant（ P〈0. 05）. Conclusion The BPV will increase when the hypertension patients with abdominal obesity,and this effect is more obvious in male patients than that in female patients.