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前交叉韧带损伤的易感基因研究进展 被引量：1

Susceptibility gene research progress of anterior cruciate ligament injury
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摘要 前交叉韧带（anterior cruciate ligament,ACL）最主要的功能是防止胫骨前移,维持膝关节结构稳定和正常运动,还有限制胫骨内旋,防止过伸以及限制内外翻的作用。焦晨等[1]发现正常ACL具有紧密排列、成波浪状走行的胶原纤维结构,且ACL组织中具有与其功能相关的连接纤维。 Anterior cruciate ligament（ ACL） rupture is one of the common injuries in clinic,especially in athletes.ACL ruptures are caused by extrinsic and intrinsic risk factors.Former research indicated that family aggregation and gene sensitivity associated with ACL injuries.Susceptibility genes were considered as intrinsic risk factors.Recently,research shows that the MMP-3 gene,COL1A1 gene COL5A1 gene and COL12A1 gene associated with ACL injury.
作者 李建 李彦林 尤志敏 黄赞
机构地区 昆明医科大学第一附属医院运动医学科
出处 《中国骨与关节杂志》 CAS 2015年第7期582-585,共4页 Chinese Journal of Bone and Joint
基金 云南省国际合作项目(2013IA004) 云南省运动医学学科带头人培养基金项目(D-201223)
关键词 前交叉韧带 创伤和损伤 胶原 基质金属蛋白酶类 基因 Anterior cruciate ligamen Wounds and injuries Collagen Matrix metalloproteinases Genes
分类号 R873 [医药卫生—运动医学]
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同被引文献21

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中国骨与关节杂志
2015年 第7期

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