2型糖尿病并发肺癌患者的临床特征探讨

Investigation of the Clinical Characteristics of Type 2 Diabetes Complicated by Lung Cancer

目的探讨2型糖尿病并发肺癌患者临床特征。方法对研究组2型糖尿病并发肺癌患者及对照组2型糖尿病未并发肺癌患者临床资料进行回顾性分析,根据两组年龄、病程、吸烟史、体质量指数、二甲双胍使用率总结2型糖尿病并发肺癌危险因素;根据研究组临床表现、治疗方法、临床疗效等总结2型糖尿病并发肺癌临床特征。结果研究组年龄、病程、吸烟人数均显著高于对照组,而其体质量指数、二甲双胍使用率则显著低于对照组,对比结果差异有统计学意义(P<0.05);研究组21例2型糖尿病并发肺癌患者中非小细胞癌所占比例最高(90.48%),其中Ⅱ期患者高达61.90%,71.43%接受外科手术治疗,经对症治疗后临床总有效率高达80.95%,对比结果差异有统计学意义(P<0.05)。结论临床医生应准确掌握2型糖尿病并发肺癌临床特征,对疑似病例积极给予各项检查确诊病情,根据患者实际情况选择正确的治疗方案,保障其生活质量及生命安全。

Objective To investigate the clinical characteristics of type 2 diabetes complicated by lung cancer.Methods A retrospective analysis was conducted on the clinical data of the study group（type 2 diabetes complicated by lung cancer） and the control group（type 2 diabetes without lung cancer）.The risk factors of type 2 diabetes complicated by lung cancer were summarized based on the age,course of disease,history of smoking,BMI,use of metfonnin in the two groups.And the clinical characteristics of type 2 diabetes complicated by lung cancer were summarized on the basis of the clinical manifestations,therapeutic method,clinical efficacy and so on in the study group.Results Compared with the control group,in the study group,the patients were much older,the course of disease was obviously longer,the number of patients with smoking was much more,while the BMI and use of metformin was significantly lower,respectively（P〈0.05）;of the 21 type 2 diabetic patients with lung cancer in the study group,non-small cell lung cancer patients had the highest percentage（90.48%）,among them patients with stage Ⅱ non-small cell lung cancer accounted for61.90%,71.43%received surgical treatment,after the symptomatic treatment,the clinical total effective rate up to 80.95%,comparing the results with statistical significance（P〈0.05）.Conclusion The clinician should accurately grasp the clinical features of type 2diabetes complicated by lung cancer,and positively give the suspected cases tests for diagnosing the disease,and give the patients proper treatment regimen in accordance with the actual condition of them for ensuring the quality of life and life safety.