补肾活血法治疗卵巢储备功能下降临床观察

Clinical Observation of Chinese Medicine Therapy of Tonifying Kidney and Invigorating Blood Circulation on Ovarian Reserve Function Decline

目的：观察补肾活血法治疗卵巢储备功能下降的临床疗效。方法：45例卵巢储备功能下降的患者,随机分为治疗组（中药补肾活血组）23例和对照组（金匮肾气片组）22例,连续用药6个月。观察两组治疗前后月经情况,临床症状积分的改善情况及血清促卵泡素（FSH）、雌二醇（E2）水平的变化。结果：两组的临床总有效率比较,治疗组优于对照组（P﹤0.05）;两组治疗前后的月经情况积分比较,治疗组优于对照组（P﹤0.05）;在改善血清FSH、E2水平方面,治疗组优于对照组（P﹤0.05）;其中治疗组有5例妊娠,并且无任何副反应的发生。结论：补肾活血中药可有效的改善卵巢储备功能,缓解临床症状,恢复月经周期、经量,疗效确切,是治疗卵巢储备功能下降的有效方法之一。

Objective：To observe the clinical curative effect of tonifying kidney and invigorating blood circulation method in the treatment of ovarian reserve function decline. Methods ：45 cases of patients with ovarian reserve function decline were randomly divided into treatment group （tonifying kidney and invigorating blood circulationChinese traditional medicine group,23 cases） and control group （Jin^ui Shenqi Tablets ,22 cases）, continuous administration for six months. Observe the two groups menstruation,the improvement of clinical symptom integral and serum follicle stimulating hormone （FSH） and estradiol （E2） levels. Results ：The clinical total effective rate of the treatment group was better than that of the control group （P 〈 0.05）. Menstruation before and after the treatment in the treatment group was better than that of control group （P 〈 0.05 ）. On improving the serum FSH and E2 levels, the treatment group was better than the control group （P 〈 0.05）. The treatment group had 5 cases of pregnancy,without any side effects. Conclusion：Tonifying kidney and invigorating blood circu- lation Chinese traditional, medicine can effectively improve the ovarian reserve function,relieve the clinical symptoms and re- store menstrual cycle and quantity. It is one of effective treatments of ovarian reserve function decline.