射干有效成分体外抗病毒实验研究

Experimental Study on Antiviral Effects of Active Components from Belamcanda Chinensis in Vitro

目的:观察射干不同有效成分体外抗病毒药效学作用;方法:采用组织细胞培养法,观察射干有效成分对呼吸道合胞病毒(RSV)、腺病毒3型(adv-3)、腺病毒7型(adv-7)、疱疹Ⅰ(HSV-1)、疱疹Ⅱ(HSV-2)、鼻病毒-3型、柯萨奇16(EV-16)等7种病毒的对抗作用;结果:体外抗病毒试验结果显示,除1号、5号外,射干不同有效成分无毒界限药液,对不同病毒RSV、Ad V-3、Ad V-7、HSV-1、HSV-2、EV-16、鼻病毒等具有一定抑制病毒致细胞病变的作用;结论:除1号、5号外,射干各有效成分分别对不同病毒RSV、Ad V-3、Ad V-7、HSV-1、HSV-2、鼻病毒、EV-16等具有不同程度的对抗作用。

Objective：To investigate the antiviral effects of different active components of Belamcanda chinensis in vitro. Methods ： The antiviral effects of different active components of Belamcanda chinensis against RSV, adv - 3, adv - 7, HSV - 1, HSV - 2,rhinovirus type -3 and EV - 16 in vitro were observed by cell culture. Results All of active compo- nents of Belamcanda chinensis except the component 1 and component 5 could exert inhibitory effects in vitro on cellular lesion induced bo, virus. Conclusion： All of active components of Belamcanda chinensis except the component 1 and component 5 have antiviral effects against RSV, adv - 3, adv - 7, HSV - 1, HSV - 2, rhinovirus type - 3 and EV - 16.