原发性高血压并糖尿病老年患者血压与靶器官损害的关联性研究

Study on the Relationship of Blood Pressure and Target Organ Damage in the Elderly Essential Hypertension Complicated with Diabetes Mellitus Patients

目的:探讨原发性高血压合并糖尿病老年患者血压与靶器官损害的关联性。方法:将本院收治的70例高血压合并糖尿病患者纳入A组,68例单纯高血压患者纳入B组,52例单纯糖尿病患者纳入C组,并将同时期的46例健康体检志愿者纳入D组。对四组患者的临床指标进行统计学分析。结果:A组患者的TC、LDL-C以及IMT水平均显著高于B、C两组;与B组比较,A组患者的24 h SBP、n SBP水平显著增高,同时24 h DBP、d DBP显著降低;A组患者的靶器官损害比例也显著高于其他组,比较差异均有统计学意义(P<0.05)。结论:原发性高血压合并糖尿病能够显著加重患者的血压变异性以及靶器官的损害程度。

Objective： To investigate the relationship of blood pressure and target organ damage in the elderly essential hypertension complicated with diabetes mellitus patients. Method： 70 cases with essential hypertension complicated with diabetes mellitus in our hospital were included in the A group, 68 cases with hypertension were divided into B group, 52 cases with diabetes mellitus were in C group, while the other 46 healthy volunteers were enrolled in the D group. Statistical analysis was performed on clinical indexes of four groups of patients. Result： The results of this study showed that the TC, LDL-C and IMT of the A group was significantly higher than that of B, C group （ P〈0.05 ） ; compared with B group, the 24 h SBP, nSBP of the A group significantly increased, while the DBP and dDBP decreased （ P〈0.05 ） ; and the proportion of target organ damage in patients was significantly higher than the other groups （ P〈0.05 ） . Conclusion： The elderly essential hypertension complicated with diabetes mellitus can significantly increase the patient＇s blood pressure variability and damage of target organ.